Diovan 32

+

(Diovan),,, 3D-: () 8000 (171) (172) (172) (172),, 40, 160 320 7 14. 1, 2, 4, 7, 20 (7 56, 98 280 (320),, 40:, DO, NVR,, 80: -....,, D / V, NVR,, 160: -.,, DX / DX, NVR,, 320: -............,, DXL, NVR - II, AT 1 II 1 - II, 2 - - AT 1 - AT 1 20000, 2,, (0,05), -...... 2, 44 () - (),,, - (,,),, (,,,.), (),,,,,.... . (II15 ...,.,,, ..,. 28.,,, 6, 28,,..,, II (62), III (36) IV (2) de la NYHA () 254. (), (),:,,, / 4,,, 13,2 27,5, - II45, (3)....... ,. 80 160 1,,, 5 10 2. NYHA,,,. ,,,, De la NYHA. . ..,,,. ,,,. . , La NYHA. ,. VALIANT 14703, /. 0510,,,, (4909), (4885), (4909). 3. 979 (19,9), 958 (19,5). -,, -, - (,,),,. ,. ,,. ,, -. 99,6. , -, 25.,, -. ,. ,. 9. . . 1. . (9497),. V SS (17). (30 /), Cl (2 /). ,, 70 (). 30,. AUC 48,, 8,,. AUC. ,,,. . AUC,,, -. . AUC. . ,. ,. . 70,. , AUC. . , AUC 2. (II, /,..,, (..,) (Cl 10 /), .., (,). (18),. II,. (,), II III. I.,,., .......,,, (),, -,,,, 1,,.,:.......... (1/10000):::,: 1,2: 4 .: -.::: 4:, -:...........,: 3,4 3. 3:,,: 0,8 a 0,4, (,,, 0,1 1 , 9,. 1,6,.,,, 0,8, 4,4 6,. 1,6, 6,4 12,9,. 50 3,9,. 0,9. 20 10,. 5, . 1 2 4,2, 4,8, 3,4,,, 50 16,6, 6,3 -... 1, - 2. - 3, - 4. (,). . ,,, -. . . :,,,,,,,. , 450.,, in vitro -,,,. (..,),,,. ,. ,. . 4. ,, 320. . 320 2. . . 12. 320 2. , 80 2. 160 2. . ,,. . . :. /. :, / 0,9. ,. . /. /. ,,. /. ... ,. / 0,9. ,,. . 12,, -,. ,,. . ,. . . (Cl 10 /). . ,. ,, Cl. . /. ,. . . . . / () /. ,. . . -. ,,,. ,,, -. ,,,, -. . ,. .